Well I have 3 Open-E systems (2DSS and 1 ISCSIR3) deployed for VI and I've never seen this issue. It's truly weird.

In /opt/VirtualIron/VirtualizationManager/system/logs/node.ip.address.log - what are the reported sizes for the disks there?

Do you mind emailing me your logs file from Open-E and log files from running getSupportInfo.py on Virtual Iron?