I've had many "system corrupted" errors, but have never lost data on the open-e systems. It is incredibly annoying that it happens (and open-e probably should switch to a filesystem like JFFS2 which is designed to be used on flash), but you just swap out the module or boot from a CD and your data is still there, safe and sound.

There's also the option of installing open-e dss (atlanta i.e. build 3511 or later) on any hard disk or RAID volume slice. I actually still like the ability to easily swap out modules, even though the stupid things keep failing. I've been looking at some USB thumb drives that use both wear-leveling and single-level cells. They're about $30 online.