Hi Couple of questions.

How have you been determining that performance is poor?

Do you have any network monitoring on the switch ports to see the level of network activity during periods of poor performance?

Have you investigated the VMs themselves? Are any of them used as a file server?

Are you running perfmon on the VMs during the poor performance to see if they may be contributing to it?

Nothing appears to be wrong with your setup. I will say this though; don't let hdparm fool you though. Just because hdparm says 400Mbs per second, does not mean your array can sustain that!

Until Open-E provides an iozone type of test, it's difficult to gauge the true performance of your disk subsystem from the local point of view. On new configuration, I will test them using Linux before deploying Open-E on the hardware.