You'd need atleast 2 nic's, each in a different subnet, on both dss and client for the iscsi bit.

Don't combine "regular" network traffic with iscsi on the same interface, so if your box has 4 nics that would be 2 for iscsi and 2 for the lan. Ofcourse, different vlans or switches for iscsi would be better but that's not cheap.