I have build my solution just 2 month ago. My bust suggestion is to use Intel/LSI card like the RMS25PB080 + the FAST PATH I/O that enable SSD cache. It works great, it's compatible with Open-e. Performance are great. My configuration is based on a entry level server with a Xeon E3 + the raid above and 6HDD in RAID 10 + SSD cache. Easy to configure and easy to manage.