I found in the meantime 3 more corrupted filesystems (1*HFS+, 2*SLES 11 SP2). Unfortunately I find this corruption only after rebooting the VMs.
We have our production data on this box, so a snapshot and revert to snapshot for invoicing data, Mail server data etc. is maybe not the best idea.
I added a 8 SSD drives to the box and moved the performance critical vmdks to this SSD datastore, the performance is now okay.
Currently I see not way to perform more alpha tests with LSI cachecade, it took too much time and effort to repair the data, the risk to lose data
is too high. To revert to a full backup after 3 weeks or more is usually not an option, to restore the data file by file and verify what's happened in between is maybe possible, but takes a lot of time.
Maybe anybody else can work with LSI to bring the software to a beta stage.