My RAID cards are

LSI Logic / Symbios Logic MegaRAID SAS 2108 [Liberator] (rev 04)
They are Supermicro AOC-USAS2LP-H8iR (which are an LSI 2108-8port PCI-e SAS-2 controller).

I have just replaced the BBU units and they are charging as we speak (these went bad about a week after I noticed I/O issues).
I'm running RAID10. Write policy is Write-Back (but it's in Write-through mode due to BBU charging) could this have the big an impact on I/O?

Read Policy: Read Ahead
Access Policy: Read-Write
Cache Policy: Direct
Disk cache Policy: Disabled

Do I change any of these settings?

Cheers
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