If combining all RAID sets to make one large Logical Volume greater then 16TB no, you can create many 16TB Logical Volumes. iSCSI-R3 does not have the 64bit option only DSS. If using DSS then yes - create each RAID set then add to existing Volume Group "VG00" to expand a particular Logical Volume or create other Logical Volumes within the same Volume Group. Remember you will need to purchase additional Storage Lic. Keys as we offer free the first 16TB. We have available 4,8,16,32 and 64TB keys.